But Dr. Newport's collection of positive anecdotes about nearly 275 patients who used coconut oil intrigued researchers at the University of South Florida's Byrd Alzheimer's Institute. CTVNews.ca Staff Published Wednesday, October 9, 2013 10:00PM EDT After studying the effects of ginkgo leaves, vitamin E and painkillers on Alzheimer's -- a disease that affects about 30 million people globally -- researchers at the University of South Florida have turned their attention to another possible natural remedy: coconut oil. Heather is committed to provide excellent and compassionate care to her patients and this award recognizes her expertise and dedication to her patients and their caregivers. CTV Health news, your source for health and fitness information, news and healthy living articles. Im extremely excited. Read more, Dr Ponnusamy was awarded a fellowship from the Alzheimer's Association International Research Grant Program. From Dr. Stephanie Steneff: The brain represents only 2% of the body's total mass, but contains 25% of the total cholesterol.Cholesterol is required everywhere in the brain as an antioxidant, an electrical insulator (in order to prevent ion leakage), as a structural scaffold for the neural network, and a functional component of all membranes. The title of the study, just released on the Internet, is Coconut Oil Attenuates the Effects ofAmyloid- on Cortical Neurons In Vitro. Rather than study the dietary effects of coconut oil, or the ketogenic diet, on neuro-degenerative diseases, this was actually anin vitrostudy that examined rodent cortical neurons exposed to AB peptide and virgin coconut oil, most likely in a petri dish or beaker, inside of a laboratory. Welcome to theByrd Alzheimers Institute website. Visit. Read the article, A new Alzheimers drug will soon be here. 20% of your purchase will benefit UsAgainstAlzheimer's, Online December 6th-7th (CODE: GIVEBACK-CZFQE), In-Store December 6th 5-7pm at the Bethesda, MD location, Alzheimer's is the 6th leading cause of death, A-LIST Pulse of the Community November 2022, Sandra Bond Chapman Ph.D. and the Importance Lifelong Brain Health - Part 1, Rebecca Chopp, Ph.D., and Her Unexpected Alzheimers Diagnosis (part 2), Rebecca Chopp, Ph.D., and Her Unexpected Alzheimers Diagnosis (part 1). While the Big Pharma interests would like to keep reminding people that there is no scientific evidence that coconut oil has any effects on Alzheimers and other neuro-degenerative diseases, there most certainly is plenty of research and documentation on the low-carb high-fatketogenic dietoriginally developed at John Hopkins Hospital back in the 1920s, before the USDA dietary guidelines came out and condemned saturated fat. 'During lockdown, getting out for a walk kept me sane' - Living well with dementia and arthritis. I think this might be a key statement made by the authors of the study: The rationale for using coconut oil as a potentialAD therapy is related to the possibility that it couldbe metabolized to ketone bodies that would provide analternative energy source for neurons, and thus compensate for mitochondrial dysfunction. (See:Alzheimers Association Warns Against Coconut Oil Member Replies Coconut Oil Gave us our Father Back!). But neither will Dr. Newport. Women who are pregnant. SPRING HILL In those first two years, her husband used chopsticks again. Dr Amanda Smith was featured in a live interview on air on channel 10 News discussing the new Alzheimers drug, Aduhelm. How physical and sensory difficulties can affect eating A new study in animals demonstrates that a diet rich in coconut oil protects against 'insulin resistance' (an impaired ability of cells to respond to insulin) in muscle and fat. Dr. Mary T. Newport. Prior to starting him on coconut oil, Newport said none of the existing medications were working. This Research Fellowship will help him to characterize the interplay between BIN1, If you can not print a copy, please call our clinic to have one mailed to you. Dr. Gulick also received an Alzheimer's Association research grant award to study how maternal and adolescent alcohol exposure increases the risk of neurodegeneration in the aged brain. Some believe coconut oil may act as an alternative energy source for the brain. . For his PhD work, he is studying the relationships between FKBP51 (a co-chaperone of HSP90) and its role in stress induced PTSD. Copyright 2022, University of South Florida. See for example: Coconut Oil and Alzheimers Disease: The News is Spreading, Film to be Made of Fathers Recovery from Alzheimers withCoconutOil, Canadian Man Swears byCoconutOilas Alzheimers Remedy, Woman with End-stage Alzheimers Sees Improvement in One Week after StartingCoconutOil, CoconutOilReverses Dementia in 100 Year Old Woman, CoconutOilReverses the Effects of Alzheimers in 50 Year Old Woman, Alzheimers andCoconutOil: Howcoconutoilgave me back my brain. Amanda Smith, MD, Clinical Director at the USF Health Byrd Alzheimer's Institute, was interviewed on the Peter Attia Drive Podcast, which focuses on physical, emotional and cognitive health topics to promote longevity. Coconut oil consumption was not significantly associated with low density lipoprotein cholesterol or triglyceride value. Convening a range of key stakeholders to take action on big issues. DrYadav, associate professor of neurosurgery and brain repair at USF Health and Director of the USF Center for Microbiome Research was recently published in theFrontiers in Aging Neuroscience. What does that mean for Florida? Coconut oil is used to allow a slightly higher level of carbohydrate intake, making the very strict diet slightly easier to follow, but still preventing the body using sugar from carbohydrates as the main energy source. Newport's testimonial, along with those from Alzheimer's care communities, has drawn doctors' and Alzheimer's specialists' attention, and in the summer of 2013, an FDA-approved, 2-year-long study began at the Byrd Institute to see just how effective coconut oil may prove to be on the 60 participants, all of which have mild to moderate . Steve Newport started taking coconut oil for his Alzheimers in May 2008. The brew's key ingredient is a type of fat known as a medium chain triglyceride. Abnormal screening visit electrocardiogram (ECG), in the opinion of the investigator. "7WqX2yY5l5Y*ZU;a\) u#k#0\yl9j m=Y%x1P4t*.l9v"|aYW_ ?8qMYQrd2 $$-Nb 8. Wl7mU!tn_+TS[rEdk But if that isnt available, because we havent eaten anything or are on a low-carbohydrate diet, then our brain cells switch to using the energy from our fat. of excellence at the University of South Florida The research was sparked by the five-year efforts of Dr. Mary Newport, who hopes to have results of the study within a year. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. His wife Mary says Alzheimers may ultimately win, but his case has given medicine a new clue. Some believe coconut oil may act as an alternative energy source for the brain. Coconut Oil Could Reverse Alzheimer's Disease. He got to the point that he had a tremor when he tried to eat or talk, she said. In 2008, she read a report on a small study of a new medicinal drink. She claims the results after he started taking the oil were remarkable. Shortly after beginning regular treatments with coconut oil, Dr. Newport's husband regained . Coconut Oil Might Reduce The Symptoms Of Type 2 Diabetes. Neuropsychiatric symptoms are commonly co-morbid with Alzheimers disease and correlate with a faster decline in patients. Research project: Mining the (-)-epicatechin metabolome for AD therapeutics. The story aired last night, you can watch it here, and talked about something new and every thrilling a clinical trial focused on coconut oil and Alzheimers disease. I . It all stems from a fat called an MCT or medium chain triglyceride. He also oiled door hinges, slow danced at a party, remembered his hairdresser's name. ;l!A^|+sWff:FB{I?-(w0eb 5 x6; ;GMD!L[j05r@ 4Nl{ 7In-i~c3}DiK;k$mREw%YlM0l/L~g)ax>kp)K6dLbY6An}QL`A _F=17?:s Dr Amanda Smith was featured in a live interview on air on channel 10 News discussing the new Alzheimers drug, Aduhelm, Dr Amanda Smith, Director of Clinical Research at the Byrd Institute, is interviewed on ABC news about the new AHEAD study. Choosing to participate in a study is an important personal decision. He gets three tablespoons of a mixture of the two oils at each meal and two tablespoons at bedtime. education. If you have a question about coconut oil and dementia, wed suggest discussing it with your GP. After five years of resistance from the medical community, Newport was able to convince the Institute researchers to launch this one-of-a-kind study of coconut oil, after receiving a $250,000 grant from a private foundation. "So in that context, the idea that you're looking for an alternate energy source through ketones is not that crazy," Mullan said. Find out the latest from Dr. Rebecca Chopp, Ph.D., built a life around a profession that prized the mind and then was unexpectedly diagnosed with Alzheimer's disease. These testimonials have helped to get grants for research at the University of South Florida (USF) Byrd Alzheimer Institute, where humane animal studies have been completed and a clinical trial of coconut oil in 65 people with mild to moderate Alzheimers disease is underway, funded. In a 2004 study, elderly subjects were fed either MCT oil or a placebo at random. Latest updates: Deal reached between feds, union for 120,000 striking public servants, U.S. to end vaccine requirements for Canadians at land border, international air travellers: officials, What you need to know about the agreement that ended the PSAC strike, Florida Panthers limit non-U.S. residents from buying Maple Leafs playoff road tickets, Man who threw stones at PM Trudeau in 2021 to be sentenced next week, Why we love taking selfies: Study says they're better at capturing the meaning of an experience, CTV News in London: Royal fans camping out on street, Michael J. Typically, people who have suffered from Alzheimer's for a decade would be in a late stage of the disease, possibly bedridden, said Mullan, of the Roskamp Institute. pathophysiology. USF Health Byrd Alzheimer's Institute began double blind Clinical Trials on 65 AD patients in April, the first clinical trials of coconut oil as a therapy! 'During lockdown, getting out for a walk kept me sane' - Living well with dementia and arthritis i~:w0/Oa4>o-/ez- ooLmM_._}|=vkzm7?o#4]-s41wVc_6y'w,S)2h0U4O:dU+lilgca=+o*gUbh$b,W7LE>_~I@9)_o6kK(+\,;k{)ooVazIz/nOb\8eX#_SK87p]d>@99y4?-fYP`[M]):Syjkk*"|CR7&S#8(. Our brains rely on glucose from carbohydrates. 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Abstract His tremors subsided. Still, some experts say the scientific rationale for coconut oil is legitimate, and worthy of investigation. Fox shares hopeful message on Parkinson's battle, Canadian Leafs fans unable to buy tickets for Florida games, 'Nothing can stop her': Paralyzed toddler a whiz in homemade wheelchair, Is 'birth tourism' a problem in Canada? The USF Health Byrd Alzheimer's Institute is dedicated to the prevention, treatment and cure. The reality: Coconut oil has been shown to raise cholesterol levels the good and the bad kinds more than other plant-based oils like olive or canola. - Dr. Jo's Super Foods Series: Coconut, aired . The MCT oils give the nerve cells a different energy source that is easier to burn.". But other days, he scoots close to her on the couch and asks about her day, she says. However, there is not enough scientific evidence to know whether this is the case. Jodie Tillman can be reached at jtillman@tampabay.com or (813) 226-3374. We respect your email privacy This is why treatments go through large clinical trials before approvalfor widespread use. |?Dt*;3,N gW1MlXN`5$Y>RY 6~oP Well deliver the latest news and information you need to know every weekday morning. They may be able to do something that they havent done in a long time, they may recall information that they havent been able to recall for quite some time. He was 54 when he was diagnosed with early onset Alzheimer's. Essentially, its an extra fuel source, Smith says. She even wrote a book she says sold more than 50,000 copies. Five things you should know about dementia, Equipment, adaptations and improvements to the home, Using technology to help with everyday life, Take part in Dementia Voice opportunities, Make your organisation more dementia friendly, All-Party Parliamentary Group on Dementia, How to reduce your risk of Alzheimer's and other dementias. At best, he said, the coconut oil may help control some symptoms of Alzheimer's. . Click to read the full story about the Mackey estate gift and the impact to USF. Joseph McMillan is a PhD student in Dr Thinakaran's lab and is interested in Coconut oil is a popular topic within our online community forum. He walked normally and he was able to start running again. Shortly after beginning regular treatments with coconut oil, Dr. Newports husband regained energy, his tremors virtually disappeared, and he got his sense of humor back. Physicians will start to recommend it to patients if they see results so we can only hope that they start to see results, said Dr. Newport. Canadian researcher, Stephen Cunnane studies brain metabolism at Universite de Sherbrooke. The diet was originally developed to treat children with epilepsy where drugs failed. The Newports' story, first told in the Tampa Bay Times in 2008, went global. The nations largest Alzheimers non-profit research institute made statements last year to its members discouraging them from trying coconut oil. Study record managers: refer to the Data Element Definitions if submitting registration or results information. He credits Mary Newport with helping drive the research. USF Health Byrd Alzheimer's Institute: Tampa, Florida: Inclusion Criteria We don't want to give a wrong impression that we have a magic solution and we have to understand why the coconut oil might be beneficial and at what doses," said Cunnane. Spurring social innovation through transformative initiatives. Not long after Steve started on the coconut oil regimen, she added MCT oil, which is available at nutrition stores. Researchers hypothesize that these ketones may provide an alternative fuel source when . His wife, Dr. Mary Newport, said she started seeing results within in days. . Half will be randomly assigned coconut oil; the other half will receive a placebo that tastes and looks like coconut oil. I'd recommend coconut oil as well if there was some good trial evidence for it.' This evidence could soon be coming from the first coconut trial now being set up by Dave Morgan, professor of molecular pharmacology and physiology and head of the USF Health Byrd Alzheimer's Institute in Florida. Doctor Sees Incredible Changes with ALS Thanks to Coconut Oil. Thiscoconut oil and Alzheimers studyenrolled 65 individuals with mild to moderate Alzheimers to measure the effects of coconut oil, versus a placebo, on the disease. A doct. That again changed public perception of this humble oil. This project might elucidate the molecular mechanisms (Clinical Trial), Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor), A Randomized, Double-Blind, Placebo-Controlled, 6 Month Cross-Over Study to Evaluate the Efficacy of Coconut Oil (Fuel for Thought) Treatment for Subjects With Mild to Moderate Alzheimer's Disease, 55 Years to 90 Years (Adult, Older Adult). But the medications do nothing to stop the disease's progression and, eventually, lose their effectiveness for most people. The Alzheimers Association receives over $230 million per year, but refuses to study anything besides pharmaceutical drugs. Byrd researchers recently received a $250,000 grant from a private foundation to conduct what is thought to be the first clinical trial of the effects of coconut oil on mild to moderate cases of Alzheimer's disease. lab, focusing on understanding the relationship between FKBP51 and Click here for Byrd Institute caregiver programs. He wanders around the house, watches television and listens to music. The goal of the Podcast is to provide important and practical information for caregivers. The Alzheimer's Caregiver Podcast just posted it's 100th episode, and based on the positive feedback and widespread impact, it will continue posting episodes to help caregivers. >FxKv6Y[-uL*^@[MT 1yWy;)u*'>q.ry3h$sl*91Y7[>kr0O]B,m%2(ott Ua8/s>s][;na/{amI)v2J0U7G:88{|=`_7(yW:Lw6x}bQ/j9OXON,x9=PkxtVf v Has significant neurological or medical disease, other than AD, that may affect cognition, for example, history or evidence of hydrocephalus, or uncontrolled hypo- or hyperthyroidism. The treatment will consist of a 1.25 oz serving size taken orally, two times daily by subjects. The study medication formula is Cognate Nutritionals Fuel for Thought. Mary Newport, now 61, is a neonatologist who runs the newborn intensive care unit at Spring Hill Regional Hospital. What does that mean for Florida? For those in Florida that would like to participate in the trial, see the flyer above. What could plug that fuel gap and keep the brain cells alive? This work may lead to new approaches to help reduce these symptoms and slow Alzheimers disease progression. The research will be carried out at the USF Health . Dr Smith was also interviewed on CW44 CBS Tampa Bay News broadcast discussing the clinical trial and benefits of the new Alzheimers drug, Aduhelm. The USF Foundation announced a $1.8 million estate gift to USF Health that will fund a womens heart health professorship, dermatology research endowment and caregiver education programs at the Byrd Alzheimers Center. facilities, provide services to people with disabilities: report, Dramatic rescue on Lake Huron in Ont. The funding for the study was from a private foundation, and not the pharmaceutical industry. Steve Newport has since suffered a setback, and his health has declined in the past year. Byrd researchers recently received a $250,000 grant from a private foundation to conduct what is thought to be the first clinical trial of the effects of coconut oil on mild to moderate cases. Changes in eating habits and food preference. Creamy Coconut Cinnamon Smoothie Towards this end the Morgan lab has used immunotherapy and gene therapy approaches. We will remember your selection for future visits; you can change your choices at any time. After this, subjects will resume with three months treatment in opposite treatment arm. Byrd researchers recently received a $250,000 grant from a private foundation to conduct what is thought to be the first clinical trial of the effects of coconut oil on mild to moderate cases. Largo lawyers death part of uncommon trend. Researchers dont know whether the problem brain cells seem to have with making energy is a cause of the disease or the result of other disease-related processes. There is no one who really stands to benefit from this except the patients. Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01883648, We're building a modernized ClinicalTrials.gov! 'It's our highway:' Researchers, Indigenous guardians monitor lake ice in N.W.T. In fact, previous studies at the USF Health Byrd Alzheimer's Institute using other treatment options have come up empty. But as a doctor, she knew anecdotal evidence is not proof. The study found that coconut oil had apositive effect ofmitochondrial size and therefore it was assumed that the coconut oil had a protective effect on the nuerons extracted from their rats. History of cancer within the last 3 years, with the exception of nonmetastatic basal cell carcinoma and squamous cell carcinoma of the skin. Use the button below to choose between help, advice and real stories. Finding effective treatments and the prevention steps to stop Alzheimers, Engaging and activating diverse communities most deeply affected by Alzheimers. In this book we look at the problems and causes of Alzheimers as they are related to an epidemic of prescription drugs being marketed to seniors, and we look at the strong evidence for dietary intervention, starting with coconut oil. Taking coconut oil is a scientifically untested and unproven treatment for Alzheimer's, dismissed by much of the scientific community. Subject must be stable on all memory enhancing medications including cholinesterase inhibitors (including donepezil, rivastigmine, and galantamine) and NMDA antagonist (memantine) for at least 3 months prior to screening and agree not to change these medications during the course of their participation, unless medically necessary. That triggered a new bout of depression. Subjects must have a Rosen Modified Hachinski Ischemic score of 4. Researchers from the USF Health Byrd Alzheimer's Institute showed that extremely low doses of THC reduce the production of amyloid beta, found in a soluble form in most aging brains, and prevent abnormal accumulation of this protein -- a process considered one of the pathological hallmarks evident early in the memory-robbing disease. The dietary interventions in both preventing and treating Alzheimers shows great promise, with a lot of documented success stories already in place. Our regular support email includes the latest dementia advice, resources, real stories and more. Subscribe to our free DayStarter newsletter. Mary Newport heard from thousands of people. Anecdotal stories suggest that coconut oil could be effective against both. But there could be another superpower tied to this super food. The claim is based on the theory that the brain cells of people with Alzheimer's disease are unable to use glucose to produce energy properly, and so the nerve cells 'starve'. When Dr. Mary Newports husband was diagnosed with early onset Alzheimers disease, she like so many of us started searching for a treatment. Niat Gebru has been working on how HSP90 co-chaperones modulate tau as we age and contribute to Alzheimers disease pathology. This is a similar idea behind the Atkins diet. Coconut oil is seen as so promising for these patients that a $250,000 grant was given by a private donor to the Byrd Alzheimer's Institute in Florida recently to study its beneficial effects. Dietary coconut oil intake was positively associated with high density lipoprotein cholesterol especially among pre-menopausal women, suggesting that coconut oil intake is associated with beneficial lipid profiles. We applaud the Byrd Institute for conducting this study. Youre using it anyway. Fuel For Thought Studied at USF Byrd Alzheimer's Institute Press Release Jul. The study partner must attend applicable clinic visits and provide information about the subject. ], Adverse events related to coconut oil usage during 6 months of treatment periods (change during a total 6 month period of time). Keywords provided by University of South Florida: Why Should I Register and Submit Results? Changes in eating habits and food preference His health declined in 2010 when his father died. And she believes she found one in coconut oil. . The Alzheimer's Association, the nation's largest advocacy group, won't endorse the use of therapies, including coconut oil, without rigorous scientific studies. With highly qualified researchers, doctors, clinicians and educators, the institute is at the forefront of Alzheimer's research and care. Josie Clarkson, a Dementia Support Worker and science writer in South London, looks at research into mushrooms and brain function. Jane shares her journey and how she overcame barriers to inspire others to move more. Dr. Danielle Gulick, PhD, a researcher at the Byrd Institute, was recently promoted to Associate Professor with Tenure. He was able to start reading again, his conversation improved dramatically and then over several months we saw improvements in his memory, Newport said. What kind of information would you like to read? Sign up to join the UsAgainstAlzheimers mailing list and receive information with the latest news and updates.

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